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| | iopydol Basic information |
| Product Name: | iopydol | | Synonyms: | 1-(2,3-Dihydroxypropyl)-3,5-diiodo-4(1H)-pyridinone;1-(2,3-Dihydroxypropyl)-3,5-diiodo-4(1H)-pyridone;Iopidol;1-(2,3-dihydroxypropyl)-3,5-diiodo-pyridin-4-one;1-(2,3-dihydroxypropyl)-3,5-diiodopyridin-4-one;1-glyceryl-3,5-diiodo-4-pyridone;iopydol;1-(2,3-dihydroxy-propyl)-3,5-diiodo-1H-pyridin-4-one | | CAS: | 5579-92-0 | | MF: | C8H9I2NO3 | | MW: | 420.97 | | EINECS: | 226-968-6 | | Product Categories: | | | Mol File: | 5579-92-0.mol |  |
| | iopydol Chemical Properties |
| | iopydol Usage And Synthesis |
| Originator | Hytrast Vial,Guerbet | | Uses | Iopydol is the X-ray contrast reagent. | | Uses | Diagnostic aid (radiopaque medium, bronchographic)
. | | Definition | ChEBI: Iopydol is a chloropyridine. | | Manufacturing Process | 50 g 4-pyridone was dissolved in 300 ml 20% hydrochloric acid and slowly
mixed with 180 g of chloroiodide in 200 ml 20% hydrochloric acid. Then the
obtained dark solution was strong alkalized with sodium hydroxide. The
solvent was removed to dryness and sodium salt diiod-4-pyridone was
obtained. It was dissolved in water, filtered and equivalent quantity of glacial
acetic acid or hydrochloric acid was added to give 3,5-diiod-4-pyridone as a
powder. 34.5 g 3,5-diiod-pyridone was dissolved in 100 ml 1 N NaOH by
heating on a water bath and added to a 15 g of monochlorohydrine added.
The mixture was heated on water bath before a dense pasty mass obtained. It
was filtered off and treated with 1 N NaOH. The obtained 1-(2,3-
dihydroxypropyl)-3,5-diiodo-4(1H)-pyridinone was recrystallized from diluted
hydrochloric acid. MP: 161°C. | | Therapeutic Function | Diagnostic aid |
| | iopydol Preparation Products And Raw materials |
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