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| | 2-(4-CHLORO-2-NITROPHENYL)ACETIC ACID Basic information | | Preparation |
| | 2-(4-CHLORO-2-NITROPHENYL)ACETIC ACID Chemical Properties |
| Melting point | 155 °C | | Boiling point | 361.2±27.0 °C(Predicted) | | density | 1.532±0.06 g/cm3(Predicted) | | pka | 3.81±0.10(Predicted) |
| | 2-(4-CHLORO-2-NITROPHENYL)ACETIC ACID Usage And Synthesis |
| Preparation | The filtrate of Step A, above, is adjusted to pH 8-9
with 2 N sodium hydroxide and is heated at 35-40 °C.
while adding a 3-6% aqueous hydrogen peroxide solu
tion until samples no longer turn dark on treatment with
2N sodium hydroxide. The tan precipitate is suspended
in 1500 ml. of water, adjusted to pH 8-9 and similarly
treated with aqueous hydrogen peroxide. The combined
reaction mixtures are then acidified with concentrated
hydrochloride acid to obtain a precipitate which are re
covered by filtration, washed 3 times with water and
dried in vacuo. The crude product (mp 145-150°C) is
recrystallized from ether to obtain 4-chloro-2-nitro
phenylacetic acid, m.p. 156-159°C. |
| | 2-(4-CHLORO-2-NITROPHENYL)ACETIC ACID Preparation Products And Raw materials |
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