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Methyl 2-phenylacetoacetate

Methyl 2-phenylacetoacetate Basic information
Uses Description
Product Name:Methyl 2-phenylacetoacetate
Synonyms:Benzeneacetic acid,CAS:16648-44-5;BMK POWDER bmk white powder 3-Oxo-2-PhenylbutanaMide BMK;16648-44-5 methyl α-acetylphenylacetate;BMK Glycidate powder 16648-44-5 manufacturer supplier suppliers factory;Methyl 2-phenylacetoacetate;BMK Glycidate Methyl 2-phenylacetoacetate;BMK Benzeneacetic acidcas16648-44-5 white powder 3-Oxo-2-PhenylbutanaMide BMK;bmk intermediates,Benzeneacetic acid
CAS:16648-44-5
MF:C11H12O3
MW:192.21
EINECS:234-232-0
Product Categories:pharmaceutical intermediate;organic interme;pharmaceutical;Additive;intermediate;Intermediate
Mol File:16648-44-5.mol
Methyl 2-phenylacetoacetate Structure
Methyl 2-phenylacetoacetate Chemical Properties
Melting point 58.5-59.0 °C
Boiling point 92-96 °C(Press: 0.6 Torr)
density 1?+-.0.06 g/cm3(Predicted)
solubility DMF: 30 mg/ml; DMSO: 50 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 50 mg/ml; Methanol: 1 mg/ml
form A crystalline solid
pka10.67±0.46(Predicted)
Safety Information
MSDS Information
Methyl 2-phenylacetoacetate Usage And Synthesis
UsesBenzeneacetic acid, a-acetyl-, methyl ester can be used as a pharmaceutical raw material.
DescriptionMethyl 2-phenylacetoacetate is an analytical reference standard categorized as a precursor in the synthesis of amphetamines and methamphetamines. This product is intended for research and forensic applications.
The Drug Enforcement Administration is proposing the control of the chemical methyl alpha-phenylacetoacetate (also known as MAPA; methyl 3-oxo-2-phenylbutanoate; methyl 2-phenylacetoacetate; [alpha]-acetyl-benzeneacetic acid, methyl ester; and CAS Number: 16648-44-5) and its optical isomers as a list I chemical under the Controlled Substances Act (CSA). Methyl alpha-phenylacetoacetate is used in clandestine laboratories to illicitly manufacture the schedule II controlled substances phenylacetone (also known as phenyl-2-propanone or P2P), methamphetamine, and amphetamine and is important to the manufacture of these controlled substances.
DescriptionMethyl 2-phenylacetoacetate (Item No. 28352) is an analytical reference standard categorized as a precursor in the synthesis of amphetamines and methamphetamines. This product is intended for research and forensic applications.
UsesD1, D2 dopamine receptor antagonist; butyrophenone antipsychotic and anti-emetic. Droperidol is a potent antagonist of dopamine subtype 2 receptor. It is an antipsychotic, which is used to treat acute behavioral anomalies. It helps to manage postoperative nausea and vomiting. Endogenous κ1b opioid receptor agonist.
PreparationMethyl phenyldiazoacetate, precursor to cyclopropanation agents, is prepared by treating methyl phenylacetate with p-acetamidobenzenesulfonyl azide in the presence of base.
Methyl 2-phenylacetoacetate Preparation Products And Raw materials
Tag:Methyl 2-phenylacetoacetate(16648-44-5) Related Product Information
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