| Company Name: |
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd
|
| Tel: |
17691182729 18161915376 |
| Email: |
1046@dideu.com |
| Products Intro: |
Product Name:3-(morpholin-4-ylmethyl)-1-[(E)-(5-nitrofuran-2-yl)methylideneamino]imidazolidine-2,4-dione
CAS:3363-58-4
Purity:98% Package:25kg
|
|
| | nifurfoline Basic information |
| Product Name: | nifurfoline | | Synonyms: | 3-[(Morpholino)methyl]-1-[(5-nitrofurfurylidene)amino]hydantoin;nifurfoline;3-(morpholin-4-ylmethyl)-1-[(E)-(5-nitrofuran-2-yl)methylideneamino]imidazolidine-2,4-dione;2,4-Imidazolidinedione, 3-(4-morpholinylmethyl)-1-[[(5-nitro-2-furanyl)methylene]amino]- | | CAS: | 3363-58-4 | | MF: | C13H15N5O6 | | MW: | 337.29 | | EINECS: | 222-131-4 | | Product Categories: | | | Mol File: | 3363-58-4.mol |  |
| | nifurfoline Chemical Properties |
| Melting point | 206°; also reported as mp 194-196° | | Boiling point | 486.5±55.0 °C(Predicted) | | density | 1.63±0.1 g/cm3(Predicted) | | pka | 5.39±0.10(Predicted) |
| | nifurfoline Usage And Synthesis |
| Originator | Furobactil,Carrion,France,1974 | | Definition | ChEBI: Nifurfoline is an imidazolidine-2,4-dione. | | Manufacturing Process | 20 g of nitrofurantoin are placed in 100 cc of dimethylformamide and the
solution is heated to 75°C to 80°C. This temperature is maintained and 100 cc
of 40% formaldehyde are added, followed by 10 g of freshly distilled
morpholine. The heating is continued for one hour, the mixture cooled and
filtered and the precipitate obtained is washed with 95% alcohol. 20 g of the
desired product are obtained as yellow crystals which melt at 206°C. | | Therapeutic Function | Antibacterial |
| | nifurfoline Preparation Products And Raw materials |
|