(2R,3R,4R)-2-羟甲基哌啶-3,4-二醇
中文名称 | (2R,3R,4R)-2-羟甲基哌啶-3,4-二醇 |
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中文同义词 | 荞麦碱;桑叶生物碱;(2R,3R,4R)-2-羟甲基哌啶-3,4-二醇;荞麦碱, >98% |
英文名称 | fagomine |
英文同义词 | fagomine;(2R)-2-(Hydroxymethyl)piperidine-3β,4α-diol;(2R)-2α-(Hydroxymethyl)piperidine-3β,4α-diol;(2R)-3β,4α-Dihydroxypiperidine-2α-methanol;1,2,5-Trideoxy-1,5-epimino-D-xylo-hexitol;(2R,3R,4R)-3,4-Dihydroxy-2-piperidinemethanol;(2R,3R,4R)-2-(Hydroxymethyl)piperidine-3,4-diol;D-FagoMine |
CAS号 | 53185-12-9 |
分子式 | C6H13NO3 |
分子量 | 147.17 |
EINECS号 | |
相关类别 | 植物提取物;对照品;标准品 -中药标准品 |
Mol文件 | 53185-12-9.mol |
结构式 |
(2R,3R,4R)-2-羟甲基哌啶-3,4-二醇 性质
熔点 | 185-186℃ |
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沸点 | 315.4±42.0 °C(Predicted) |
密度 | 1.279 |
酸度系数(pKa) | 14.16±0.60(Predicted) |
LogP | -0.880 (est) |
Glycosidase
Fagomine (D-fagomine) is an iminosugar that has been shown to selectively agglutinate Enterobacteriales in vitro. Fagomine selectively agglutinates fimbriated enterobacteria (e.g., E.coli ) and inhibits their adhesion to the intestinal mucosa; the reason for this is probably related to its structural similarity with lectin-binding saccharides (e.g., mannose). Fagomine is capable of altering this effect of high-fat high-sucrose diet (HFHS) on the proportion of Enterobacteriales and E.coli .
Fagomine (D-fagomine) is a natural iminosugar that counteracts the short-term effects of a high-energy-dense diet on body weight, fasting blood glucose levels and the proportion of gut Enterobacteriales. Compare to the standard group, rats fed high-fat high-sucrose diet (HFHS) with Fagomine (D-fagomine) gain significantly less weight (15.3%) than those fed HFHS (20.9%).
安全信息
更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
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2024/04/30 | HY-13005 | Fagomine | 1 mg | 2045元 | |
2024/04/30 | HY-13005 | (2R,3R,4R)-2-羟甲基哌啶-3,4-二醇 Fagomine | 53185-12-9 | 5mg | 4500元 |