Bz-5-ME-2'-脱氧胞苷亚磷酰胺单体
| 中文名称 | Bz-5-ME-2'-脱氧胞苷亚磷酰胺单体 |
|---|---|
| 中文同义词 | 5-甲基-N4-苯甲酰基脱氧胞苷亚磷酰胺;N-苯甲酰基-5'-O-[二(4-甲氧基苯基)苯基甲基]-2'-脱氧-5-甲基-胞苷 3'-[2-氰基乙基 N,N-二异丙基亚磷酰胺];5甲基DC;BZ-5-ME-2'-DC 亚磷酰胺单体;BZ-5-ME-2'-脱氧胞苷亚磷酰胺单体;N4-苯甲酰基-5-甲基-5'-O-DMT-脱氧胞苷亚磷酰胺;(2R,3S,5R)-5-(4-BENZAMIDO-5-METHYL-2-OXOPYRIMIDIN-1(2H)-YL)-2-((BIS(4-METHOXYPHENYL)(PHENYL)METHOXY)METHYL)TETRAHYDROFURAN-3-YL (2-CYANOETHYL) DIISOPROPYLPHOSPHORAMIDITE;AC-5-ME-2'-脱氧尿苷亚磷酰胺单体 |
| 英文名称 | 5'-O-(4,4'-DIMETHOXYTRITYL)-5-METHYL-N4-BENZOYL-2'-DEOXYCYTIDINE-3'-(2-CYANOETHYL-N,N-DIISOPROPYL)PHOSPHORAMIDITE |
| 英文同义词 | N-blocked-5'-O-DMT CED methyldeoxycytidine phosphoramidite;5'-O-(4,4'-DIMETHOXYTRITYL)-5-METHYL-N4-BENZOYL-2'-DEOXYCYTIDINE-3'-(2-CYANOETHYL-N,N-DIISOPROPYL)PHOSPHORAMIDITE;5-methyldeoxycytidine-ce*phosphoramidite for cycl;5''-O-(4,4''-dimethoxytrityl)-5-methyl-N4-benzoyl-2''-deoxycytidine-3''-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite;N4-Benzoyl-2'-deoxy-5'-O-DMT-5-methylcytidine 3'-CE phosphoramidite;5'-O-(4,4'-DiMethoxytrityl)-N4-benzoyl-2'-deoxy-5-Methylcytidine-3'- O-(O-2-cyanoethyl-N,N-diisopropylaMino) phosphoraMidite;8: PN: US20040014050 PAGE;N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-methyl-cytidine 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] |
| CAS号 | 105931-57-5 |
| 分子式 | C47H54N5O8P |
| 分子量 | 847.93 |
| EINECS号 | 804-903-8 |
| 相关类别 | 亚磷酰胺(phosphoramidite);化学试剂 |
| Mol文件 | 105931-57-5.mol |
| 结构式 |  |
Bz-5-ME-2'-脱氧胞苷亚磷酰胺单体 性质
| 储存条件 | Store at -20°C |
|---|---|
| 溶解度 | DMSO：250 mg/mL（294.84 mM；需要超声波） |
| 酸度系数(pKa) | 8.68±0.40(Predicted) |
Bz-5-ME-2'-脱氧胞苷亚磷酰胺单体可用作医药合成中间体。有研究开发了一种新的，简化的商业过程，用于制备核苷亚磷酰胺类化合物，这是用于基于寡核苷酸的药物自动固相支持合成的关键原料。