| Company Name: |
Shanghai Hongye Biotechnology Co. Ltd
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| Tel: |
400-9205774 |
| Email: |
sales@glpbio.cn |
| Products Intro: |
Product Name:20-carboxy Leukotriene B4
CAS:80434-82-8
Purity:>98% Package:1mg;10mg;50mg;100mg;
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| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
|
| Tel: |
18818260767 |
| Email: |
sales@chemegen.com |
| Products Intro: |
Product Name:20-carboxy Leukotriene B4
CAS:80434-82-8
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
|
| Company Name: |
amyjetsci
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| Tel: |
027-59626688 18771149750 |
| Email: |
sales@amyjet.com |
| Products Intro: |
Product Name:20-carboxy Leukotriene B4
Package:1mg
|
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| | 20-CARBOXY-LEUKOTRIENE B4 Basic information |
| Product Name: | 20-CARBOXY-LEUKOTRIENE B4 | | Synonyms: | 20-CARBOXY-LEUKOTRIENE B4;20-COOH-LTB4;5S,12R-DIHYDROXY-6Z,8E,10E,14Z-EICOSATETRAENE-1,20-DIOIC ACID;(5S,6Z,8E,10E,12R,14Z)-5,12-dihydroxyicosa-6,8,10,14-tetraenedioic acid;20-hydroxy-20-oxoleukotriene B4;6,8,10,14-Eicosatetraenedioic acid, 5,12-dihydroxy-, (5S,6Z,8E,10E,12R,14Z)- | | CAS: | 80434-82-8 | | MF: | C20H30O6 | | MW: | 366.45 | | EINECS: | | | Product Categories: | Fatty Acids;Leukotrienes;Lipids | | Mol File: | 80434-82-8.mol |  |
| | 20-CARBOXY-LEUKOTRIENE B4 Chemical Properties |
| Boiling point | 588.3±50.0 °C(Predicted) | | density | 1.151±0.06 g/cm3(Predicted) | | Fp | 14℃ | | storage temp. | −20°C | | solubility | DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS pH 7.2: 1 mg/ml | | pka | 4.66±0.10(Predicted) |
| | 20-CARBOXY-LEUKOTRIENE B4 Usage And Synthesis |
| Description | 20-carboxy LTB4 is a metabolite of LTB4 in human neutrophils. In human leukocytes, LTB4 is inactivated by the enzyme LTB4 20-hydroxylase. The resulting 20-hydroxy LTB4 is further oxidized to 20-carboxy LTB4. LTB4 metabolism in isolated rat hepatocytes also results in production of 20-carboxy LTB4 along with other ω-oxidation products. The biological activity of 20-carboxy LTB4 is only about 2.6% compared to that of LTB4 in causing PMNL degranulation. | | Uses | 20-COOH-LTB4 is a leukotriene B4 metabolite and substrate for β-oxidation pathways. | | Definition | ChEBI: A member of the class of leukotrienes that is leukotriene B4 in which the terminal methyl group has undergone formal oxidation to the corresponding carboxylic acid. |
| | 20-CARBOXY-LEUKOTRIENE B4 Preparation Products And Raw materials |
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