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acediasulfone sodium

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Company Name: Dideu Industries Group Limited
Tel: +86-29-89586680 +86-15129568250
Email: 1026@dideu.com
Products Intro: Product Name:acediasulfone sodium
CAS:127-60-6
Purity:99.9% Package:1g;1.1USD Remarks:FDA GMP CEP Approved Manufacturer
Company Name: Shaanxi Dideu Medichem Co. Ltd  
Tel: 029-81124267 15229202216
Email: 1073@dideu.com
Products Intro: Product Name:acediasulfone sodium
CAS:127-60-6
Purity:99% Package:25KG
Company Name: Shanghai New Union Textra Import & Export Co., Ltd  
Tel: +861-348-227-9455
Email: zhou@pharmchemical.com
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acediasulfone sodium manufacturers
acediasulfone sodium Basic information
Product Name:acediasulfone sodium
Synonyms:acediasulfone sodium;N-[4-[(4-Aminophenyl)sulfonyl]phenyl]glycine sodium salt;acediasulfone sodium USP/EP/BP
CAS:127-60-6
MF:C14H15N2NaO4S
MW:330.33
EINECS:204-852-6
Product Categories:
Mol File:127-60-6.mol
acediasulfone sodium Structure
acediasulfone sodium Chemical Properties
Safety Information
MSDS Information
acediasulfone sodium Usage And Synthesis
OriginatorSolfone ,Bracco
Manufacturing Process24.8 g of 4,4'-diaminodiphenyl sulfone, 150 g of methyl chloroacetate and 150 ml of ethanol are refluxed together and refluxed for 24 hours. The alcohol and excess methyl chloroacetate are then distilled off on a steam bath under reduced pressure. The residue consisting of the hydrochloride salt of 4-amino- 4'-(carbomethoxymethylamino)diphenyl sulfone is mixed with of alcoholic solution containing 2.5 g lithium hydroxide and refluxed for 4 hours on the steam bath. Most of the alcohol is removed by distillation and the residual lithium salt of 4-amino-4'-(carboxymethylamino)diphenyl sulfone taken up water. The solution is filtered and dilute HCl added until no more separation occurs. The 4-amino-4'-(carboxymethylamino)diphenyl sulfone thus obtained is collected and dried.
The sodium salt of 4-amino-4'-(carboxymethylamino)diphenyl sulfone is prepared by dissolving the free acid in an aqueous solution containing one equivalent of sodium hydroxide and evaporating the solution to dryness in vacuo.
Therapeutic FunctionAntibacterial
acediasulfone sodium Preparation Products And Raw materials
Raw materialsMethyl chloroacetate-->Sodium hydroxide-->Hydrochloric acid-->Lithium hydroxide-->4,4'-Diaminodiphenylsulfone
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