Bis(2-chloroethoxy)methane
Product identifier
- Product name: Bis(2-chloroethoxy)methane
- CBnumber: CB3440463
- CAS: 111-91-1
- EINECS Number: 203-920-2
- Synonyms: Bis(2-chloroethoxy)methane
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 400-158-6606
Classification of the substance or mixture
Acute toxicity - Category 3, Oral
Acute toxicity - Category 4, Dermal
Acute toxicity - Category 2, Inhalation
Specific target organ toxicity – single exposure, Category 1
Specific target organ toxicity – repeated exposure, Category 2
Label elements
Pictogram(s)
-
Signal word
Danger
H301 Toxic if swallowed
H312 Harmful in contact with skin
H330 Fatal if inhaled
H370 Causes damage to organs
H373 May cause damage to organs through prolonged or repeated exposure
P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P284 [In case of inadequate ventilation] wear respiratory protection.
P301+P316 IF SWALLOWED: Get emergency medical help immediately.
P321 Specific treatment (see ... on this label).
P330 Rinse mouth.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P317 Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P316 Get emergency medical help immediately.
P320 Specific treatment is urgent (see ... on this label).
P308+P316 IF exposed or concerned: Get emergency medical help immediately.
P319 Get medical help if you feel unwell.
P405 Store locked up.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards
no data available
Substance
- Product name: Bis(2-chloroethoxy)methane
- Synonyms: Bis(2-chloroethoxy)methane
- CAS: 111-91-1
- EC number: 203-920-2
- MF: C5H10Cl2O2
- MW: 173.04
Description of first aid measures
If inhaledMove the victim into fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration and consult a doctor immediately. Do not use mouth to mouth resuscitation if the victim ingested or inhaled the chemical.
Take off contaminated clothing immediately. Wash off with soap and plenty of water. Consult a doctor.
Rinse with pure water for at least 15 minutes. Consult a doctor.
Rinse mouth with water. Do not induce vomiting. Never give anything by mouth to an unconscious person. Call a doctor or Poison Control Center immediately.
Most important symptoms and effects, both acute and delayed
ACUTE/CHRONIC HAZARDS: Toxic by inhalation and ingestion; Strong irritant. (NTP, 1992)
Indication of any immediate medical attention and special treatment needed
no data available
Extinguishing media
To fight fire, use alcohol foam, foam, CO2 or dry chemical.
Specific Hazards Arising from the Chemical
Not Flammable. (NTP, 1992)
Advice for firefighters
Wear self-contained breathing apparatus for firefighting if necessary.
NFPA 704
| HEALTH | 2 | Intense or continued but not chronic exposure could cause temporary incapacitation or possible residual injury (e.g. diethyl ether, ammonium phosphate, iodine) | |
| FIRE | 1 | Materials that require considerable preheating, under all ambient temperature conditions, before ignition and combustion can occur. Includes some finely divided suspended solids that do not require heating before ignition can occur. Flash point at or above 93.3 °C (200 °F). (e.g. mineral oil, ammonia) | |
| REACT | 0 | Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2) | |
| SPEC. HAZ. |
Personal precautions, protective equipment and emergency procedures
Avoid dust formation. Avoid breathing mist, gas or vapours.Avoid contacting with skin and eye. Use personal protective equipment.Wear chemical impermeable gloves. Ensure adequate ventilation.Remove all sources of ignition. Evacuate personnel to safe areas.Keep people away from and upwind of spill/leak.
Environmental precautions
Prevent further spillage or leakage if it is safe to do so. Do not let the chemical enter drains. Discharge into the environment must be avoided.
Methods and materials for containment and cleaning up
Collect and arrange disposal. Keep the chemical in suitable and closed containers for disposal. Remove all sources of ignition. Use spark-proof tools and explosion-proof equipment. Adhered or collected material should be promptly disposed of, in accordance with appropriate laws and regulations.
Precautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Materials which are toxic as stored or which can decomp into toxic components due to contact with heat, moisture, acid, or acid fumes, should be stored in cool, well-ventilated place, out of direct rays of sun, away from areas of high fire hazard and should be periodically inspected and monitored.
Control parameters
Occupational Exposure limit valuesno data available
no data available
Exposure controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures
Eye/face protectionWear tightly fitting safety goggles with side-shields conforming to EN 166(EU) or NIOSH (US).
Wear fire/flame resistant and impervious clothing. Handle with gloves. Gloves must be inspected prior to use. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.
If the exposure limits are exceeded, irritation or other symptoms are experienced, use a full-face respirator.
no data available
Information on basic physicochemical properties
- Physical stateOil
- ColourColorless liquid
- Odour
no data available
- Melting point/freezing point
-37 °C. Atm. press.:101.4 kPa.
- Boiling point or initial boiling point and boiling range
220 °C. Atm. press.:101.4 kPa.
- Flammability
no data available
- Lower and upper explosion limit/flammability limit
no data available
- Flash point
103 °C. Atm. press.:101.5 kPa.
- Auto-ignition temperature
395 °C. Atm. press.:> 1 013.3 - < 1 014.9 hPa.
- Decomposition temperature
no data available
- pH
2.3.
- Kinematic viscosity
kinematic viscosity (in mm2/s) = 3.74. Temperature:20°C.
- SolubilityChloroform (Sparingly), Methanol (Slightly)
- Partition coefficient n-octanol/water
log Pow = 1.6. Temperature:25 °C.
- Vapour pressure1 at 53 °C (Weast, 1986)
- Density and/or relative density
1.23 g/cm3. Temperature:20 °C.
- Relative vapour density
5.9 (Air= 1)
- Particle characteristics
no data available
Reactivity
Slightly soluble in water.
Chemical stability
no data available
Possibility of hazardous reactions
Combustible.BIS(2-CHLOROETHOXY)METHANE, [LIQUID], the b-chloroethyl acetal of formaldehyde, is incompatible with oxidizing agents.
Conditions to avoid
no data available
Incompatible materials
Oxidizing materials.
Hazardous decomposition products
When heated to decomp it emits... fumes of /hydrogen chloride/.
Acute toxicity
- Oral: LD50 Rat (Sherman) oral 65 mg/kg
- Inhalation: LC50 - rat (male/female) - > 0.05 - <= 0.5 mg/L air.
- Dermal: LD50 - rat (female) - > 1 000 - < 2 000 mg/kg bw.
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
CLASSIFICATION: D: not classifiable as to human carcinogenicity. BASIS FOR CLASSIFICATION: No human data and no animal data. HUMAN CARCINOGENICITY DATA: inadequate. AMIMAL CARCINOGENICITY DATA: Inadequate.
Reproductive toxicity
no data available
STOT-single exposure
no data available
STOT-repeated exposure
no data available
Aspiration hazard
no data available
Toxicity
- Toxicity to fish: LC50 - Danio rerio (previous name: Brachydanio rerio) - 50.2 mg/L - 96 h.
- Toxicity to daphnia and other aquatic invertebrates: EC50 - Daphnia magna - 201 mg/L - 48 h.
- Toxicity to algae: EC50 - Desmodesmus subspicatus (previous name: Scenedesmus subspicatus) - 35 mg/L - 72 h.
- Toxicity to microorganisms: EC50 - activated sludge of a predominantly domestic sewage - > 100 mg/L - 3 h. Remarks:Respiration rate.
Persistence and degradability
Bis(2-chloroethoxy)methane underwent 0% biodegradation using settled domestic wastewater as an inoculum; biodegradation remained at 0% through three subcultures. Bis(2-chloroethoxy)methane was thus listed as being not biodegraded under the conditions of the method, the lowest of a three tier rating system(1,2). When the influent to a full scale activated sludge treatment system was spiked with 0.24 ug/l bis(2-chloroethoxy)methane, 60% of the pollutant was removed(3); however, it was not reported if removal was due to biodegradation or some other removal process(SRC).
Bioaccumulative potential
An estimated BCF of 4 was calculated for bis(2-chloroethoxy)methane(SRC), using a water solubility of 7,800 mg/l(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).
Mobility in soil
The Koc of bis(2-chloroethoxy)methane is estimated as 32(SRC), using a water solubility of 7,800 mg/l(1) and a regression-derived equation(2). According to a classification scheme(3), this estimated Koc value suggests that bis(2-chloroethoxy)methane is expected to have very high mobility in soil(SRC).
Other adverse effects
no data available
Disposal methods
ProductThe material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
UN Number
ADR/RID: no data available
IMDG: no data available
IATA: no data available
UN Proper Shipping Name
ADR/RID: no data available
IMDG: no data available
IATA: no data available
Transport hazard class(es)
ADR/RID: 6.1 (For reference only, please check.)
IMDG: 6.1 (For reference only, please check.)
IATA: 6.1 (For reference only, please check.)
Packing group, if applicable
ADR/RID: III (For reference only, please check.)
IMDG: III (For reference only, please check.)
IATA: III (For reference only, please check.)
Environmental hazards
ADR/RID: No
IMDG: No
IATA: No
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
Safety, health and environmental regulations specific for the product in question
European Inventory of Existing Commercial Chemical Substances (EINECS)Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.