2-(4-CHLOROPHENYL)ETHYL ISOTHIOCYANATE synthesis
- Product Name:2-(4-CHLOROPHENYL)ETHYL ISOTHIOCYANATE
- CAS Number:17608-10-5
- Molecular formula:C9H8ClNS
- Molecular Weight:197.68
96989-50-3
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$48.00/250mg
156-41-2
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17608-10-5
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$26.00/1g
Yield:-
Reaction Conditions:
in N,N-dimethyl-formamide at 55; for 1.5 h;Molecular sieve;
Steps:
To a solution of 0.25 M di-pyridyl-thiocarbonate in DMF (stored on molecular sieves 3A) (1.05 eq) was added 0.1 M amine (free base) 0.1 M in DMF (1eq). The reaction mixture was heated at 55 °C for 1.5 h.
References:
Maingot, Lucie;Elbakali, Jamal;Dumont, Julie;Bosc, Damien;Cousaert, Nicolas;Urban, Agathe;Deglane, Gaelle;Villoutreix, Bruno;Nagase, Hideaki;Sperandio, Olivier;Leroux, Florence;Deprez, Benoit;Deprez-Poulain, Rebecca [European Journal of Medicinal Chemistry,2013,vol. 69,p. 244 - 261]
