4-Methyl-3-nitrobenzene-1-sulfonyl chloride synthesis
- Product Name:4-Methyl-3-nitrobenzene-1-sulfonyl chloride
- CAS Number:616-83-1
- Molecular formula:C7H6ClNO4S
- Molecular Weight:235.64
88-72-2
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$15.00/25g
5329-14-6
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$13.50/100G
616-83-1
123 suppliers
$27.00/1g
Yield:-
Reaction Conditions:
with chlorosulfonic acid in (2S)-N-methyl-1-phenylpropan-2-amine hydrate
Steps:
12 2-Nitrotoluene-4-sulfonyl chloride
EXAMPLE 12 2-Nitrotoluene-4-sulfonyl chloride 137.1 g (1.0 mol) of o-nitrotoluene are added dropwise to 535.9 g (4.6 mol) of chlorosulfonic acid and 2 g of sulfamic acid such that the temperature does not exceed 40° C. The mixture is then stirred at 40° C. for 1 hour and slowly heated to 105° C. It is then stirred at 105° C. for 6 hours, cooled and added dropwise to ice water at 0 to 5° C. The precipitated crystals are filtered off with suction and washed with ice water. 236.1 g of 2-nitrotoluene-4-sulfonyl chloride (water content 10.8%), corresponding to 210.6 g (89% of theory), having a melting point of 40° C. are obtained.
References:
Hoechst Aktiengesellschaft US5136043, 1992, A
88-72-2
247 suppliers
$15.00/25g
616-83-1
123 suppliers
$27.00/1g
98-59-9
588 suppliers
$9.00/5g
616-83-1
123 suppliers
$27.00/1g
119-32-4
253 suppliers
$15.00/25g
616-83-1
123 suppliers
$27.00/1g