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ETHYL 2-METHYL-2-PHENOXYPROPANOATE synthesis

8synthesis methods
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Yield:18672-04-3 77%

Reaction Conditions:

Stage #1: 1,1,1-trichloro-2-methyl-2-propanol;phenolwith sodium hydroxide in acetone at 20;
Stage #2: ethanolwith thionyl chloride for 6 h;Heating;

References:

Tanaka;Tamai;Mukaiyama;Hirabayashi;Muranaka;Ishikawa;Akahane;Akahane [Bioorganic and medicinal chemistry,2001,vol. 9,# 12,p. 3265 - 3271]

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