Guanidine, cyano-, (E)- (9CI) synthesis

9synthesis methods

Product Name:Guanidine, cyano-, (E)- (9CI)
CAS Number:780722-26-1
Molecular formula:C2H4N4
Molecular Weight:84.08

10191-60-3 Synthesis

N-Cyanoimido-S,S-dimethyl-dithiocarbonate

10191-60-3
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780722-26-1
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Yield:-

Reaction Conditions:

in ethanol;

Steps:

2 Compound 2-1

Example 2 Synthesis of Representative Compounds Compound 2-1 To the methyl amino compound 1-7 (from Example 1, 15 mg, 0.036 mmol) in absolute ethanol at room temperature was added dimethyl cyanodithioiminocarbonate (0.072 mmol). The reaction was heated on an 80° C. hotplate in a sealed vessel for 72 hours. The reaction mixture was then purified on silica gel eluding with ethyl acetate/hexanes 1:3 (R_f=0.10). The solvent was removed in vacuo to afford the N-cyanoguanidine 2-1 as a white solid (5 mg). MS (M+1) 465.

References:

US2002/32196,2002,A1