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Clindamycin Hcl

CAS No.
21462-39-5
Chemical Name:
Clindamycin Hcl
Synonyms
CLINDAMYCIN HCL;ClindaMycin-d3;CLEOCIN;Dalacin;7(S)-CHLORO-7-DEOXYLINCOMYCIN;Clindamycin hydrochloride, nonsterile;U-21251F;dalacina;Dalacin S;Clidamacin
CBNumber:
CB00127148
Molecular Formula:
C18H34Cl2N2O5S
Molecular Weight:
461.44
MDL Number:
MFCD07793327
MOL File:
21462-39-5.mol
MSDS File:
SDS
Last updated:2024-05-18 08:51:57

Clindamycin Hcl Properties

Melting point 141°C
storage temp. 2-8°C
solubility H2O: 50 mg/mL, clear, colorless
color White to Off-White
BRN 4070786
Stability Hygroscopic
InChIKey AUODDLQVRAJAJM-XJQDNNTCSA-N
SMILES [C@@H]1([C@@H]([C@H](C)Cl)NC(=O)[C@@H]2C[C@@H](CCC)CN2C)[C@H](O)[C@H](O)[C@H]([C@@H](SC)O1)O.Cl |&1:0,1,2,8,10,17,19,21,22,r|
CAS DataBase Reference 21462-39-5(CAS DataBase Reference)
FDA UNII T20OQ1YN1W

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H317-H319-H362
Precautionary statements  P260-P263-P280-P302+P352-P305+P351+P338-P308+P313
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-37/39
WGK Germany  2
RTECS  GF2275000
10
HS Code  29419000

Clindamycin Hcl price More Price(38)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich C5269 Clindamycin hydrochloride lincosamide antibiotic 21462-39-5 10mg $99.2 2024-03-01 Buy
Sigma-Aldrich C5269 Clindamycin hydrochloride lincosamide antibiotic 21462-39-5 50mg $287 2024-03-01 Buy
Sigma-Aldrich C5269 Clindamycin hydrochloride lincosamide antibiotic 21462-39-5 100mg $482 2024-03-01 Buy
Sigma-Aldrich C2250000 Clindamycin hydrochloride European Pharmacopoeia (EP) Reference Standard 21462-39-5 c2250000 $220 2024-03-01 Buy
Tocris 4822 Clindamycin hydrochloride ≥98%(HPLC) 21462-39-5 50 $305 2021-12-16 Buy
Product number Packaging Price Buy
C5269 10mg $99.2 Buy
C5269 50mg $287 Buy
C5269 100mg $482 Buy
C2250000 c2250000 $220 Buy
4822 50 $305 Buy

Clindamycin Hcl Chemical Properties,Uses,Production

Description

Clindamycin is a semisynthetic derivative of lincomycin and was introduced in the 1960s as an antibiotic. It is usually available as one of three salts: clindamycin phosphate, Clindamycin Hcl, or clindamycin nicotinamide. These salt forms are all prodrugs of clindamycin, but once inside the body or applied to the skin, they are rapidly converted to active clindamycin by hydrolysis. All three salt forms of clindamycin have the same antimicrobial spectrum and effectiveness.

Clindamycin phosphate salts are usually used for intravenous, intramuscular, and topical formulations of clindamycin. Clindamycin Hcl salts are usually used for oral forms of clindamycin, and clindamycin nicotinamide is another topical form of clindamycin.

Uses

Clindamycin is used to treat a wide variety of bacterial infections. It is an antibiotic that works by stopping the growth of bacteria.This antibiotic treats only bacterial infections. It will not work for virus infections (such as common cold, flu). Using any antibiotic when it is not needed can cause it to not work for future infections.

Absorption

Pharmacokinetic studies with a 150 mg oral dose of Clindamycin Hcl in 24 normal adult volunteers showed that clindamycin was rapidly absorbed after oral administration. An average peak serum concentration of 2.50 mcg/mL was reached in 45 minutes; serum concentrations averaged 1.51 mcg/mL at 3 hours and 0.70 mcg/mL at 6 hours. Absorption of an oral dose is virtually complete (90%), and the concomitant administration of food does not appreciably modify the serum concentrations; serum concentrations have been uniform and predictable from person to person and dose to dose. Pharmacokinetic studies following multiple doses of Clindamycin Hcl for up to 14 days show no evidence of accumulation or altered metabolism of drug. Doses of up to 2 grams of clindamycin per day for 14 days have been well tolerated by healthy volunteers, except that the incidence of gastrointestinal side effects is greater with the higher doses.

Clindamycin Hcl Preparation Products And Raw materials

Global( 664)Suppliers
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Baoji Guokang Bio-Technology Co., Ltd.
0917-3909592 13892490616 gksales1@gk-bio.com China 9329 58
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Wuhan Marco Pharmaceutical Technology Co., Ltd.
+86-86-18572802410 +8618572802410 sales@marcopht.com China 55 58
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+86-371-86557731 +86-13613820652 info@fdachem.com China 18214 58
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Related articles

View Lastest Price from Clindamycin Hcl manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
CLINDAMYCIN HCL pictures 2023-12-19 CLINDAMYCIN HCL
58207-19-5
US $0.00-0.00 / kg 1kg 99.9 500000kg Hebei Kingfiner Technology Development Co.Ltd
Clindamycin HCl pictures 2023-09-17 Clindamycin HCl
21462-39-5
US $0.00-0.00 / kg 25kg 99% 1000kg Wuhan Marco Pharmaceutical Technology Co., Ltd.
  • CLINDAMYCIN HCL pictures
  • CLINDAMYCIN HCL
    58207-19-5
  • US $0.00-0.00 / kg
  • 99.9
  • Hebei Kingfiner Technology Development Co.Ltd
  • Clindamycin HCl pictures
  • Clindamycin HCl
    21462-39-5
  • US $0.00-0.00 / kg
  • 99%
  • Wuhan Marco Pharmaceutical Technology Co., Ltd.

Clindamycin hydrochloride Spectrum

Clindamycin IMP CLINDAMYCIN HYDROCHLORIDE, LINCOSAMI Clindamycin hydrochloride, nonsterileUSP, ≥ 860 μg/mg (2S-TRANS)-METHYL 7-CHLORO-6,7,8-TRIDEOXY-6[[(1-METHYL-4-PROPYL-2-PYRROLIDINYL)CARBONYL]AMINO]-1-THIO-L-THREO-ALPHA-D-GALACTO-OCTOPYRANOSIDE (7S)-7-CHLORO-7-DEOXYLINCOMYCIN HYDROCHLORIDE 7(S)-CHLORO-7-DEOXYLINCOMYCIN HCL 7[S]-CHLORO-7-DEOXYLINCOMYCIN HYDROCHLORIDE CLEOCIN HYDROCHLORIDE CLINDAMYCIN HYDROCHLORIDE U-21251F (2S-trans)-Methyl 7-chloro-6,7,8-trideoxy-6-[[(1-methyl-4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio-L-threo-alpha-D-galacto-octothiopyranoside monohydrochloride (7S)-7-Chloro-7-deoxylincomycin hydrochloride, Cleocin 7-chloro-7-deoxylincomycinhydrochloride clindimycinhydrochloride clindomycinhydrochloride dalacina Clidamacin Dalacin S Panancocin (2S-trans)-Methyl 7-Chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-Methyl-4-propyl-2- pyrrolidinyl]carbonyl]aMino]-1-thio- ClindaMycin hydrochloride Antipyrotic ClindaMycin HCL USP30 EP5 BP2007 Clindamycin Base & Phosphate Clindamycin hydrochloride,(7S)-7-Chloro-7-deoxylincomycin hydrochloride, Cleocin 7-Chloro-7-deoxylincoMycin hydrochloride, 7-ChlorolincoMycin hydrochloride (L-threo-α-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-, hydrochloride (1:1)) Clindaymcin Hydrochloride BP98,USP25,EP97 L-threo-.alpha.-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-(2S,4R)-1-methyl-4-propyl-2-pyrrolidinylcarbonylamino-1-thio-, monohydrochloride CLINDAMYCINHYDROCHLORIDE,CRYSTAL CLINDAMYCINHYDROCHLORIDE,USP Clindamycin hydrochloride, Antibiotic for Culture Media Use Only CLINDAMYCIN HC Lujiemycin monohydrochloride,(2s-methyl-4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio CLINDAMYCIN HCI (7S)-7CHLORO-7-DEOXYLINCOMYCIN HCL (2S-trans)-Methyl 7-Chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2- pyrrolidinyl]carbonyl]amino]-1-thio-L-threo-α-D-galactooctopyranoside Hydrochloride Clindamycin hydrochloride Solution, 1000ppm Clindamycin Impurity 14(Clindamycin Phosphate EP Impurity E) (4R)-N-[(1S,2S)-2-chloro-1-[(3R,4R,6R)-3,4,5-trihydroxy-6-(methylthio)-2-oxanyl]propyl]-1-methyl-4-propyl-2-pyrrolidinecarboxamide hydrochloride Methyl-7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-L-threo-α-D-galacto-octopyranoside hydrochloride Clindamycin hydrochloride CRS Clinimycin HCl Sobelin HCl indamycin HydrochL Clindamycin hydrochloride solution in Methanol, 1000ug/ml Clindamycin hydrochloride (USP, EP, oral grade) (2S,4R)-N-((1S,2S)-2-chloro-1-((2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(methylthio)tetrahydro-2H-pyran-2-yl)propyl)-1-methyl-4-propylpyrrolidine-2-carboxamide hydrochloride Clindamycin hydrochloride salt lindamycin hydrochloride Clindamycin HydrochlorideQ: What is Clindamycin Hydrochloride Q: What is the CAS Number of Clindamycin Hydrochloride Q: What is the storage condition of Clindamycin Hydrochloride Q: What are the applications of Clindamycin Hydrochloride Clindamycin 13C D3 HydrochlorideQ: What is Clindamycin 13C D3 Hydrochloride Q: What is the CAS Number of Clindamycin 13C D3 Hydrochloride Q: What is the storage condition of Clindamycin 13C D3 Hydrochloride Q: What are the applications of Clindamycin 13C D3 Hydrochloride Clindamycin Hydrochloride (Cleocin) Clindamycin hydrochloride API CLEOCIN CLINDAMYCIN HCL Clindamycin hydrochloride, nonsterile Dalacin