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Betamethasone Dipropionate

CAS No.
5593-20-4
Chemical Name:
Betamethasone Dipropionate
Synonyms
BETAMETHASONE DIPROPIONATE;BetaMethasone dipropionat;diprolene;diprosone;Betamethasone 17;S 3440;Psorion;Maxivate;diprosis;Diprophos
CBNumber:
CB00127834
Molecular Formula:
C28H37FO7
Molecular Weight:
504.6
MDL Number:
MFCD00072035
MOL File:
5593-20-4.mol
MSDS File:
SDS
Last updated:2024-04-19 20:05:26

Betamethasone Dipropionate Properties

Melting point 178 °C
alpha D26 +65.7° (dioxane)
Boiling point 603.2±55.0 °C(Predicted)
Density 1.1481 (estimate)
refractive index 69 ° (C=1, Dioxane)
storage temp. 2-8°C
solubility Practically insoluble in water, freely soluble in acetone and in methylene chloride, sparingly soluble in ethanol (96 per cent).
pka 12.87±0.70(Predicted)
color White to Pale Yellow
Merck 1180
InChIKey CIWBQSYVNNPZIQ-JCOVECCMSA-N
SMILES C([C@]1([C@H](C[C@@]2([H])[C@]3([H])CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C)C)OC(=O)CC)(=O)COC(=O)CC |&1:1,2,4,6,16,18,20,23,r|
CAS DataBase Reference 5593-20-4(CAS DataBase Reference)
FDA UNII 826Y60901U

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS08
Signal word  Danger
Hazard statements  H360FD-H373
Precautionary statements  P202-P260-P280-P308+P313-P405-P501
Safety Statements  22-24/25
WGK Germany  2
RTECS  TU4058000
HS Code  29372290
Toxicity LD50 ipr-mus: 103 mg/kg NIIRDN 6,753,82

Betamethasone Dipropionate price More Price(22)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich B1152 Betamethasone 17,21-dipropionate ≥97.0% 5593-20-4 1g $276 2024-03-01 Buy
Sigma-Aldrich 1067704 Betamethasone dipropionate 5593-20-4 125mg $358 2024-03-01 Buy
Sigma-Aldrich Y0001925 Betamethasone dipropionate for system suitability A European Pharmacopoeia (EP) Reference Standard 5593-20-4 Y0001925 $212 2023-06-20 Buy
Sigma-Aldrich Y0001416 Betamethasone dipropionate for peak identification European Pharmacopoeia (EP) Reference Standard 5593-20-4 y0001416 $220 2024-03-01 Buy
Sigma-Aldrich B1152 Betamethasone 17,21-dipropionate ≥97.0% 5593-20-4 100mg $53.4 2024-03-01 Buy
Product number Packaging Price Buy
B1152 1g $276 Buy
1067704 125mg $358 Buy
Y0001925 Y0001925 $212 Buy
Y0001416 y0001416 $220 Buy
B1152 100mg $53.4 Buy

Betamethasone Dipropionate Chemical Properties,Uses,Production

Description

Betamethasone dipropionate is a glucocorticoid steroid with anti-inflammatory and immunosuppressive abilities. It is applied as a topical cream, ointment, lotion or gel (Diprolene) to treat itching and other skin conditions such as eczema.

Physical properties

Betamethasone dipropionate is a white to almost white crystalline powder.

Brand name

Alphatrex,Del-Beta,Diprosone

Clinical Use

Betamethasone Dipropionate is a "super high potency" corticosteroid used to treat inflammatory skin conditions such as dermatitis, eczema and psoriasis.

Side effects

Minor side effects include dry skin and mild, temporary stinging when applied.Please get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

52092-14-5
5593-20-4
Synthesis of Betamethasone Dipropionate from (11β,16β)-9-BroMo-11-hydroxy-16-Methyl-17,21-bis(1-oxopropoxy)pregna-1,4-diene-3,20-dione

Betamethasone Dipropionate Preparation Products And Raw materials

Global( 412)Suppliers
Supplier Tel Email Country ProdList Advantage
APOLLO HEALTHCARE RESOURCES
+6596580999 sales@apollo-healthcare.com.sg Singapore 400 58
Nanjing Shizhou Biotechnology Co., Ltd
+86-15850508050 +86-15850508050 sean.lv@synzest.com China 323 58
Hebei Dangtong Import and export Co LTD
+8615632927689 admin@hbdangtong.com China 984 58
Hebei Kangcang new material Technology Co., LTD
+8615713292910 Nancy@kangcang.com.cn China 341 58
Shaanxi TNJONE Pharmaceutical Co., Ltd
+8618740459177 sarah@tnjone.com China 1142 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21688 55
Hubei XinRunde Chemical Co., Ltd.
+8615102730682 bruce@xrdchem.cn CHINA 566 55
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28180 58
Xiamen AmoyChem Co., Ltd
+86-592-6051114 +8618959220845 sales@amoychem.com China 6387 58

View Lastest Price from Betamethasone Dipropionate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Betamethasone Dipropionate pictures 2021-12-14 Betamethasone Dipropionate
5593-20-4
US $10.00 / g/Bag 10g 99 100KG Wuhan Demeikai Biotechnology Co., Ltd
Betamethasone dipropionate pictures 2021-09-29 Betamethasone dipropionate
5593-20-4
US $0.00 / Kg/Bag 1KG 97%-103%; USP 100kg WUHAN FORTUNA CHEMICAL CO., LTD
Betamethasone Dipropionate pictures 2021-07-09 Betamethasone Dipropionate
5593-20-4
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
BETAMETHASONE 17,21-DI-PROPIONATE BETAMETHASONE 17-ALPHA,21-DIPROPIONATE 1,4-PREGNADIEN-9-ALPHA-FLUORO-16-BETA-METHYL-11-BETA, 17,21-TRIOL-3,20-DIONE 17,21-DIPROPIONATE 9ALPHA-FLUORO-16BETA-METHYL-11BETA,17ALPHA,21-TRIHYDROXY-1,4-PREGNADIENE-3,20-DIONE 17,21-DIPROPIONATE Betamethasonediproprionate 9--Fluoro-16--methyl-11,17,21-trihydroxy-1,4-pregnadiene-3,20-dione17,21-dipropionate BETANMETHASONE DIPROPIONATE BETAMETHASONEDIPROPIONATE,MICRONIZEDPOWDER,USP Diprophos Maxivate Pregna-1,4-diene-3,20-dione, 9-fluoro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)-, (11β,16β)- Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17,21-trihydroxy-16β-methyl-, 17,21-dipropionate (7CI, 8CI) Psorion Rinderon DP S 3440 Sch 11460 β-Methasone 17,21-dipropionate 9alpha-Fluoro-11beta,17alpha,21-trihydroxy-16beta-methyl-1,4-pregnadiene-3,20-dione 17,21-Dipropionate 17,21-Di(propionyloxy)-9-fluoro-11β-hydroxy-16β-methylpregna-1,4-diene-3,20-dione [(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-(2-propanoyloxyacetyl)-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate [(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-(2-propanoyloxyethanoyl)-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate propionic acid [(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-3-keto-10,13,16-trimethyl-17-(2-propionyloxyacetyl)-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] ester Betamethasone 17,21-dipropionate,9α-Fluoro-16β-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione 17,21-dipropionate Betamethasone Dipropionate (125 mg) Betamethasone 17,21- 9a-fluoro-16b-methyl-11b,17a,21-trihydroxy-1,4-pregnadiene-3,20-dione 17,21-dipropionate Betamethasone dipropionate for peak identification Betamethasone dipropionate for system suitability 17,21 betaMethasone dipropionate ester diproderm diprosis 9-fluoro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17,21-di(propionate) Betanmethasone Dipronate Pregna-1,4-Diene-3,20-Dione,9-Fluoro-11-Hydroxy-16-Methyl-17,21-Bis(1-Oxopropoxy)-,(11Beta,16Beta)- (11-beta,16-beta)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione-17,21-dipropionate Betamethaasone Dipropionate 99% High Purity Raw Powder Betamethason 17, 21-Dipropionate CAS 5593-20-4 Betamethasone dipropionate (B1040000)Q: What is Betamethasone dipropionate (B1040000) Q: What is the CAS Number of Betamethasone dipropionate (B1040000) Betamethasone dipropionate for peak identification (Y0001416) Betamethasone dipropionate for system suitability A (Y0001925) Betamethasone DipropionateQ: What is Betamethasone Dipropionate Q: What is the CAS Number of Betamethasone Dipropionate Q: What is the storage condition of Betamethasone Dipropionate Betamethasone Dipropionate (1067704) AT-13387 lactate ATI-13387A ATI-13387AU propanoic acid [2-[(8R,9S,10R,11S,13S,14R,16S,17R)-8-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-(1-oxopropoxy)-6,7,9,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] ester Betamethasone 17,21-dipropionate, ≥97.0% Betamethasone 17,21-dipropionate(5593-20-4) Betamethasone dipropionate for peak identification CRS Betamethasone 17,21-Dipropionate > Betamethasone dipropionate CRS Diprolene AF Betamethasone dipropionate for system suitability A (8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-(2-(propionyloxy)acetyl)-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl propionate Anhydrous Beclometasone Dipropionate Betamethasone dipropionate solution in Acetonitrile, 100μg/mL Pregna-1,4-diene-3,20-dione,9-fluoro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)-, (11b,16b)- Betamethasone 17,21-dipropionate USP/EP/BP