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Diminutol

CAS No.
361431-33-6
Chemical Name:
Diminutol
Synonyms
NG72;Diminutol;1-Butanol, 2-[[6-[(3-aminophenyl)thio]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3-methyl-, (2R)-
CBNumber:
CB02756303
Molecular Formula:
C19H26N6OS
Molecular Weight:
386.51
MDL Number:
MFCD23160286
MOL File:
361431-33-6.mol
Last updated:2023-05-21 10:59:17

Diminutol Properties

storage temp. Store at -20°C
solubility DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml; Ethanol: 20 mg/ml
form A crystalline solid

Diminutol price More Price(10)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 18237 Diminutol ≥98% 361431-33-6 500μg $49 2024-03-01 Buy
Cayman Chemical 18237 Diminutol ≥98% 361431-33-6 1mg $92 2024-03-01 Buy
Cayman Chemical 18237 Diminutol ≥98% 361431-33-6 5mg $380 2024-03-01 Buy
Cayman Chemical 18237 Diminutol ≥98% 361431-33-6 10mg $665 2024-03-01 Buy
Usbiological 447266 Diminutol 361431-33-6 5mg $651 2021-12-16 Buy
Product number Packaging Price Buy
18237 500μg $49 Buy
18237 1mg $92 Buy
18237 5mg $380 Buy
18237 10mg $665 Buy
447266 5mg $651 Buy

Diminutol Chemical Properties,Uses,Production

Description

Diminutol is a cell-permeable purine derivative that inhibits the NADP-dependent oxidoreductase, NQO1 (Ki = 1.72 μM), to destabilize microtubules and disrupt mitosis. At 50 μM, it directly affects tubulin polymerization in Xenopus egg extracts without interfering with the activity of Cdk1, DNA replication, or actin polymerization.

Uses

Diminutol is a cell-permeable purine analog that inhibits NQ01 and blocks mitotic spindle assembly.

Uses

Diminutol is a cell-permeable purine derivative that inhibits the NADP-dependent oxidoreductase, NQO1 (Ki = 1.72 μM), to destabilize microtubules and disrupt mitosis. At 50 μM, it directly affects tubulin polymerization in Xenopus egg extracts without interfering with the activity of Cdk1, DNA replication, or actin polymerization.[Cayman Chemical]

Diminutol Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 32)Suppliers
Supplier Tel Email Country ProdList Advantage
Aladdin Scientific
+1-833-552-7181 sales@aladdinsci.com United States 52927 58
BOC Sciences 16314854226 info@bocsci.com United States 9926 65
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
DC Chemicals 021-58447131 13564518121 sales@dcchemicals.com China 9414 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8141 58
Energy Chemical 021-58432009 400-005-6266 marketing@energy-chemical.com China 44941 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 8740 58
Diminutol 1-Butanol, 2-[[6-[(3-aminophenyl)thio]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3-methyl-, (2R)- NG72 361431-33-6