CGP 78608 HYDROCHLORIDE
- CAS No.
- 206648-13-7
- Chemical Name:
- CGP 78608 HYDROCHLORIDE
- Synonyms
- CGP78608HCl;CGP 78608 hydrochlor;CGP 78608 HYDROCHLORIDE;Phosphonic acid, P-[(1S)-1-[[(7-bromo-1,2,3,4-tetrahydro-2,3-dioxo-5-quinoxalinyl)methyl]amino]ethyl]-;((1S)-1-(((7-Bromo-1,2,3,4-tetrahydro-2,3-dioxo-5-quinoxalinyl)methyl)amino)ethyl]phosphonicacidhydrochloride;[(1S)-1-[[(7-BROMO-1,2,3,4-TETRAHYDRO-2,3-DIOXO-5-QUINOXALINYL)METHYL]AMINO]ETHYL]PHOSPHONIC ACID HYDROCHLORIDE
- CBNumber:
- CB4141516
- Molecular Formula:
- C11H13BrN3O5P
- Molecular Weight:
- 378.12
- MDL Number:
- MFCD06798371
- MOL File:
- 206648-13-7.mol
| Density | 1.757±0.06 g/cm3(Predicted) |
|---|---|
| storage temp. | Store at RT |
| solubility | <41.46mg/ml in 2.2eq. NaOH |
| pka | 0.66±0.10(Predicted) |
| FDA UNII | E53G4C95XT |
CGP 78608 HYDROCHLORIDE price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Tocris | 1493 | CGP78608hydrochloride ≥98%(HPLC) | 206648-13-7 | 10 | $227 | 2021-12-16 | Buy |
| Tocris | 1493 | CGP78608hydrochloride ≥98%(HPLC) | 206648-13-7 | 50 | $936 | 2021-12-16 | Buy |
| TRC | C583563 | CGP78608 | 206648-13-7 | 25mg | $305 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0009990 | CGP 78608 HYDROCHLORIDE 95.00% | 206648-13-7 | 5MG | $497.49 | 2021-12-16 | Buy |
| ApexBio Technology | B6762 | CGP78608hydrochloride | 206648-13-7 | 50mg | $1399 | 2021-12-16 | Buy |
CGP 78608 HYDROCHLORIDE Chemical Properties,Uses,Production
Uses
CGP 78608 is a potent and selective NMDA antagonist.
Definition
ChEBI: CGP 78608 is a phosphonic acid in which the hydrogen attached to phosphorous is substituted by a 1-{[(7-bromo-2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-5-yl)methyl]amino}ethyl group. Potent and selective NMDA antagonist that acts through the glycine site (IC50 = 5 nM). Displays >500-fold selectivity over kainate and AMPA receptors (IC50 values are 2.7 and 3 muM respectively). Anticonvulsant in vivo following systemic administration. It has a role as a NMDA receptor antagonist and an anticonvulsant. It is a quinoxaline derivative, an organobromine compound, a secondary amino compound and a member of phosphonic acids. It contains a CGP 78608(1+).
Biological Activity
Potent and selective NMDA antagonist that acts through the glycine site (IC 50 = 5 nM). Displays > 500-fold selectivity over kainate and AMPA receptors (IC 50 values are 2.7 and 3 μ M respectively). Anticonvulsant in vivo following systemic administration. Also available as part of the NMDA Receptor - Glycine Site Tocriset™ .
CGP 78608 HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
CGP 78608 HYDROCHLORIDE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8449 | 60 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8141 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44941 | 58 |
| Changzhou Furuisi Biotechnology Co., Ltd | 0519-85524369 | 3477467573@qq.com | China | 8618 | 58 |
| Shanghai Universal Biotech Co.,Ltd | 18768175414 | gaojun@univ-bio.com | China | 24998 | 58 |
| ApexBio Technology | -- | sales@apexbt.com | United States | 6254 | 58 |