ChemicalBook >> CAS DataBase List >>D-(+)-Norephedrine

D-(+)-Norephedrine

CAS No.
37577-28-9
Chemical Name:
D-(+)-Norephedrine
Synonyms
(1S,2S)-2-amino-1-phenyl-1-propanol;C02343;dl-propadrine;(+)-Norephedrin;D-(+)-NOREPHEDRINE;d-NOREPHEDRINE BASE;dl-NOREPHEDRINE BASE;d-Phenylpropanolamine;dl-phenylpropanolamine;D-(+)-Norephedrine [DD]
CBNumber:
CB4667296
Molecular Formula:
C9H13NO
Molecular Weight:
151.21
MDL Number:
MFCD00064411
MOL File:
37577-28-9.mol
Last updated:2023-05-15 10:43:31

D-(+)-Norephedrine Properties

Melting point 51-54 °C(lit.)
alpha 40 º (c=7, 1M HCl)
Boiling point 288.1±20.0 °C(Predicted)
Density 1.071±0.06 g/cm3(Predicted)
Flash point >230 °F
storage temp. 2-8°C
pka 12.07±0.45(Predicted)
optical activity [α]20/D +40°, c = 7 in 1 M HCl
BRN 2802896
CAS DataBase Reference 37577-28-9(CAS DataBase Reference)
FDA UNII 7875H6443P
NIST Chemistry Reference (1S,2r)-(+)-norephedrine(37577-28-9)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazard Codes  Xn
Risk Statements  22-36/37/38
Safety Statements  26
WGK Germany  3
3-8-10

D-(+)-Norephedrine Chemical Properties,Uses,Production

Uses

(1S,2R)-(+)-Norephedrine Hydrochloride is used in preparation of pyrrolopyridines as ERK inhibitors useful in treatment of diseases.

Definition

ChEBI: (+)-norephedrine is an amphetamine that is propylbenzene substituted by a hydroxy group at position 1 and by an amino group at position 2 (the 1S,2R-stereoisomer). It is a member of amphetamines and a phenethylamine alkaloid.

D-(+)-Norephedrine Preparation Products And Raw materials

(1S,2R)-(+)-2-AMINO-1-PHENYL-1-PROPANOL (1S,2R)-2-AMINO-1-PHENYL-1-PROPANOL (1S,2R)-(+)-PHENYLPROPANOLAMINE (1S,2R)-(+)-NOREPHEDRINE D-(+)-NOREPHEDRINE ERYTHRO-ALPHA-(1-AMINOETHYL)BENZYL ALCOHOL (1S,2R)-(+)-Norephedrine [DD] D-(+)-Norephedrine [DD] (R*,S*)-(±)-alpha-(1-aminoethyl)benzyl alcohol dl-NOREPHEDRINE BASE d-NOREPHEDRINE BASE (1S,2R)-(+)-NOREPHEDRINE 96+% (IS,2R)-d-Norephedrine Base Benzenemethanol, .alpha.-(1R)-1-aminoethyl-, (.alpha.S)-rel- PHENYLPROPANOLAMINEBASE dl-phenylpropanolamine dl-propadrine (1S,2R)-2-Amino-1-phenyl-1-propanol, erythro-α-(1-aminoethyl)benzyl alcohol, D-(+)-Norephedrine, Phenylpropanolamine d-Phenylpropanolamine erythro-α-(1-aminoethyl)benzyl alcohol C02343 (1S,2R)-(+)-2-Amino-1-phenyl-1-propanol (1S,2R)-(+)-Phenylpropanolamine DLNKOYKMWOXYQA-VXNVDRBHSA-N Benzenemethanol, α-[(1R)-1-aminoethyl]-, (αS)- (1S,2R)-(+)-NorephedrineQ: What is (1S,2R)-(+)-Norephedrine Q: What is the CAS Number of (1S,2R)-(+)-Norephedrine (+)-Norephedrin (1S,2S)-2-amino-1-phenyl-1-propanol 37577-28-9 14838-15-1 Ephedrine Derivatives Asymmetric Synthesis Chiral Auxiliaries Pharmaceutical Intermediates