ChemicalBook >> CAS DataBase List >>L-745,870 TRIHYDROCHLORIDE

L-745,870 TRIHYDROCHLORIDE

L-745,870 TRIHYDROCHLORIDE structure

CAS No.: 158985-00-3

Chemical Name:: L-745,870 TRIHYDROCHLORIDE

Synonyms: 3HCl;L 745870;L 745870,L745870;L-745,870 trihydroch;L-745,870 TRIHYDROCHLORIDE;3-[[4-(4-Chlorophenyl)-1-piperazinyl]methyl]-1H-pyrrolo[2,3-b]pyridine;1H-Pyrrolo[2,3-b]pyridine, 3-[[4-(4-chlorophenyl)-1-piperazinyl]methyl]-;3-(4-[4-CHLOROPHENYL]PIPERAZIN-1-YL)-METHYL-1H-PYRROLO[2,3-B]PYRIDINE TRIHYDROCHLORIDE

CBNumber:: CB6481216

Molecular Formula:: C18H19ClN4

Molecular Weight:: 326.82

MDL Number:: MFCD00932830

MOL File:: 158985-00-3.mol

MSDS File:: SDS

Last updated:2023-05-18 11:31:10

Request For Quotation

L-745,870 TRIHYDROCHLORIDE Properties

Boiling point	571.4±50.0 °C(Predicted)
Density	1.31±0.1 g/cm3(Predicted)
storage temp.	Desiccate at +4°C
solubility	DMSO:16.5(Max Conc. mg/mL);50.49(Max Conc. mM)
pka	8.20±0.20(Predicted)
FDA UNII	J3OLN3XSX7

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P280-P301+P312-P302+P352-P305+P351+P338

L-745,870 TRIHYDROCHLORIDE price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Tocris	1002	L-745,870trihydrochloride ≥99%(HPLC)	158985-00-3	50	$634	2021-12-16	Buy
American Custom Chemicals Corporation	API0003103	3-((4-(4-CHLOROPHENYL)PIPERAZIN-1-YL)METHYL)-1H-PYRROLO[2,3-B]PYRIDINE 95.00%	158985-00-3	10MG	$665.81	2021-12-16	Buy
American Custom Chemicals Corporation	API0003103	3-((4-(4-CHLOROPHENYL)PIPERAZIN-1-YL)METHYL)-1H-PYRROLO[2,3-B]PYRIDINE 95.00%	158985-00-3	50MG	$1073.29	2021-12-16	Buy
American Custom Chemicals Corporation	API0003103	3-((4-(4-CHLOROPHENYL)PIPERAZIN-1-YL)METHYL)-1H-PYRROLO[2,3-B]PYRIDINE 95.00%	158985-00-3	1G	$1529.85	2021-12-16	Buy
ChemScene	CS-0003281	L-745870 99.88%	158985-00-3	5mg	$82	2021-12-16	Buy

Product number	Packaging	Price	Buy
1002	50	$634	Buy
API0003103	10MG	$665.81	Buy
API0003103	50MG	$1073.29	Buy
API0003103	1G	$1529.85	Buy
CS-0003281	5mg	$82	Buy

L-745,870 TRIHYDROCHLORIDE Chemical Properties,Uses,Production

Uses

L-745,870 is a drug which acts as a dopamine receptor antagonist selective for the D4 subtype, and has antipsychotic effects in animal models, though it was not effective in human trials.

Definition

ChEBI: 3-[[4-(4-chlorophenyl)-1-piperazinyl]methyl]-1H-pyrrolo[2,3-b]pyridine is a member of piperazines.

Biological Activity

A highly potent and selective D 4 dopamine receptor antagonist; L-745,870 has K i values of 0.51, 2300 and 960 nM for D 4 , D 3 and D 2 subtypes respectively and > 1000-fold selectivity over 5-HT 2 , D 1 and D 5 receptors.

L-745,870 TRIHYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

L-745,870 TRIHYDROCHLORIDE Suppliers

Global( 38)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49739	58
Zibo Hangyu Biotechnology Development Co., Ltd	+86-0533-2185556 +8617865335152	Mandy@hangyubiotech.com	China	11013	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43348	58
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15848	69
Tianjin heowns Biochemical Technology Co., Ltd.	400 638 7771	sales@heowns.com	China	14443	57
UHN Shanghai Research & Development Co., Ltd.	021-58958002 18930822973	SALES@UHNSHANGHAI.COM	China	977	58
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8449	60
Tianjin Kailiqi Biotechnology Co., Ltd.	15076683720	klq@cw-bio.com	China	3444	55

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
TargetMol Chemicals Inc.	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	58
Zibo Hangyu Biotechnology Development Co., Ltd	58
LEAPCHEM CO., LTD.	58
3B Pharmachem (Wuhan) International Co.,Ltd.	69
Tianjin heowns Biochemical Technology Co., Ltd.	57
UHN Shanghai Research & Development Co., Ltd.	58
EMMX Biotechnology LLC	60
Tianjin Kailiqi Biotechnology Co., Ltd.	55

158985-00-3(L-745,870 TRIHYDROCHLORIDE)Related Search:

hypochlorous acid 1-(2,9-diazabicyclo[4.3.0]nona-2,4,7,10-tetraen-7-yl)-N,N-dimethyl-methanamine 1-(4-Chlorophenyl)piperazine dihydrochloride 1H-Pyrrolo[2,3-b]pyridine, 3-(1-piperazinylmethyl)- 3-METHYL-7-AZAINDOLE

3-([4-(4-CHLOROPHENYL)PIPERAZIN-1-YL]METHYL)-1H-PYRROLO(2,3-B)PYRIDINE HYDROCHLORIDE 7-Azaindole L-745,870 TRIHYDROCHLORIDE

1of2

L-745,870 TRIHYDROCHLORIDE 3HCl 3-(4-[4-CHLOROPHENYL]PIPERAZIN-1-YL)-METHYL-1H-PYRROLO[2,3-B]PYRIDINE TRIHYDROCHLORIDE L 745870 3-[[4-(4-Chlorophenyl)-1-piperazinyl]methyl]-1H-pyrrolo[2,3-b]pyridine 1H-Pyrrolo[2,3-b]pyridine, 3-[[4-(4-chlorophenyl)-1-piperazinyl]methyl]- L-745,870 trihydroch L 745870,L745870 158985-00-3 C18H22Cl4N4 C18H19N4Cl3HCl