2-CHLORO-ALPHA-[2-DIMETHYLAMINOETHYL]BENZHYDROL HYDROCHLORIDE
![2-CHLORO-ALPHA-[2-DIMETHYLAMINOETHYL]BENZHYDROL HYDROCHLORIDE Structure](CAS/GIF/511-13-7.gif)
- CAS No.
- 511-13-7
- Chemical Name:
- 2-CHLORO-ALPHA-[2-DIMETHYLAMINOETHYL]BENZHYDROL HYDROCHLORIDE
- Synonyms
- ulo;sk74;ulone;sl501;detigon;coldrin;refugal;bayer-186;bayerb-186;pectolitan
- CBNumber:
- CB7744592
- Molecular Formula:
- C17H21Cl2NO
- Molecular Weight:
- 326.26
- MDL Number:
- MFCD00079013
- MOL File:
- 511-13-7.mol
- MSDS File:
- SDS
| Melting point | 190-191° |
|---|---|
| storage temp. | Hygroscopic, Refrigerator, under inert atmosphere |
| solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| color | White to Off-White |
| Stability | Hygroscopic |
| CAS DataBase Reference | 511-13-7(CAS DataBase Reference) |
| FDA UNII | 69QQ58998Y |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS09 |
|---|---|
| Signal word | Warning |
| Hazard statements | H410-H302 |
| Precautionary statements | P264-P270-P301+P312-P330-P501-P273-P391-P501 |
| Hazard Codes | T |
| Risk Statements | 25 |
| Safety Statements | 36/37/39-45 |
| RIDADR | 3249 |
| RTECS | DC7600000 |
| HazardClass | 6.1(b) |
| PackingGroup | III |
| Toxicity | LD50 orally in rats: 350 mg/kg; s.c. in mice: 95 mg/kg (Lorenz) |
2-CHLORO-ALPHA-[2-DIMETHYLAMINOETHYL]BENZHYDROL HYDROCHLORIDE price More Price(10)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 006963 | Clofedanol Hydrochloride | 511-13-7 | 50mg | $460 | 2021-12-16 | Buy |
| TRC | C586920 | ClofedanolHydrochloride | 511-13-7 | 2.5g | $965 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC20497 | Clofedanol hydrochloride | 511-13-7 | 25mg | $1000 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC20497 | Clofedanol hydrochloride | 511-13-7 | 50mg | $1600 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | HCH0106065 | 2-CHLORO-ALPHA-[2-DIMETHYLAMINOETHYL]BENZHYDROL HYDROCHLORIDE 95.00% | 511-13-7 | 500MG | $1963.5 | 2021-12-16 | Buy |
2-CHLORO-ALPHA-[2-DIMETHYLAMINOETHYL]BENZHYDROL HYDROCHLORIDE Chemical Properties,Uses,Production
Originator
Abehol,Pliva
Uses
A centrally-acting cough suppressant. It has local anesthetic and antihistamine properties, and may have anticholinergic effects at high doses.
Definition
ChEBI: Chlophedianol hydrochloride is a diarylmethane.
Manufacturing Process
To a suspension of 330.0 g of sodamide (moistened with toluene) in 1500 ml
of absolute ether, a solution of 1080.0 g of o-chlorobenzophenone and 350.0
g of acetonitrile in 3500 ml of absolute ether was gradually added dropwise,
with stirring, such that the reaction temperature adjusted itself to 28°-30°C.
The reaction mixture was stirred for 12 to 15 h at room temperature and was
then added carefully to some ice water. The resulting solution was extracted 3
times with ether. The ether solution was washed with water, dried over
Na2SO4, filtered, and finally concentrated. When 1 L of petroleum ether was
added, 1240.0 g (96% of theoretical) of β-phenyl-β-o-chlorophenylhydroacrylonitrile (melting point 90°-92°C) precipitated.
500.0 g of the β-phenyl-β-o-chlorophenyl-hydroacrylonitrile were dissolved in
3 L of methanol and hydrogenated in the presence of 50.0 g of Raney cobalt
at a temperature of 60°-70°C and a pressure of 80-85 ATM. Two moles of
hydrogen were absorbed, and after separation of the methanolic solution from
the catalyst, 450.0 g of 1-o-chlorophenyl-1-phenyl-3-aminopropanol-1 of
melting point 117°C were obtained.
Catalytic methylation of 1-o-chlorophenyl-1-phenyl-3-aminopropanol-1
(hydrogenation in the presence of 2.2 mol of formaldehyde in aqueous
methanol with Raney nickel catalyst) yielded 450.0 g of l-o-chlorophenyl-1-
phenyl-3 dimethylaminopropanol-1 of melting point 120°C.
In practice it is usually used as hydrochloride.
brand name
Ulo (3M Pharmaceuticals).
Therapeutic Function
Antitussive
2-CHLORO-ALPHA-[2-DIMETHYLAMINOETHYL]BENZHYDROL HYDROCHLORIDE Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21689 | 55 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| TopScience Biochemical | 00852-68527855 | info@itopbiochem.com | China Hong Kong | 902 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49391 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | 18192627656 | 1012@dideu.com | China | 2931 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 28659 | 58 |
| AFINE CHEMICALS LIMITED | 0571-85134551 | info@afinechem.com | CHINA | 15377 | 58 |
View Lastest Price from 2-CHLORO-ALPHA-[2-DIMETHYLAMINOETHYL]BENZHYDROL HYDROCHLORIDE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
![2-CHLORO-ALPHA-[2-DIMETHYLAMINOETHYL]BENZHYDROL HYDROCHLORIDE USP/EP/BP pictures](/ProductImageEN/2021-05/Small/f34f762b-7ebe-4afa-b5fa-fbeb748dae06.jpg) |
2021-06-01 | 2-CHLORO-ALPHA-[2-DIMETHYLAMINOETHYL]BENZHYDROL HYDROCHLORIDE USP/EP/BP
511-13-7
|
US $1.10 / g | 1g | 99.9% | 100Tons min | Dideu Industries Group Limited | |
 |
2020-04-25 | Chlophedianol hydrochloride
511-13-7
|
US $0.01-1.00 / KG | 1KG | 99% | 50 tons | Shaanxi Dideu Medichem Co. Ltd | |
![2-CHLORO-ALPHA-[2-DIMETHYLAMINOETHYL]BENZHYDROL HYDROCHLORIDE pictures](https://img.chemicalbook.com/ProductImageEN/2019-7/Small/abb8a7b5-6a78-4db6-8adc-4c73430ad797.png) |
2019-07-12 | 2-CHLORO-ALPHA-[2-DIMETHYLAMINOETHYL]BENZHYDROL HYDROCHLORIDE
511-13-7
|
US $1.00 / KG | 1KG | 99% | 1ton | Career Henan Chemical Co |
-
- 2-CHLORO-ALPHA-[2-DIMETHYLAMINOETHYL]BENZHYDROL HYDROCHLORIDE USP/EP/BP
511-13-7
- US $1.10 / g
- 99.9%
- Dideu Industries Group Limited
-
- Chlophedianol hydrochloride
511-13-7
- US $0.01-1.00 / KG
- 99%
- Shaanxi Dideu Medichem Co. Ltd
-
- 2-CHLORO-ALPHA-[2-DIMETHYLAMINOETHYL]BENZHYDROL HYDROCHLORIDE
511-13-7
- US $1.00 / KG
- 99%
- Career Henan Chemical Co