カコジル酸 化学特性,用途語,生産方法
外観
白色～わずかにうすい黄色, 結晶～結晶性粉末
溶解性
水, エタノールに可溶。水及びエタノールに溶ける。
解説
dimethylarsinic acid．C2H7O2As(138.00)．カコジル酸は，酸化カコジルを過酸化水素などで酸化すると得られる．潮解性の固体．融点195～196 ℃．エタノールに易溶，水に可溶．両性化合物で，金属水酸化物，ハロゲン化水素とも塩をつくる．毒性が強い．森北出版「化学辞典（第2版）
用途
薬理研究用、カコジル酸塩合成原料。
化学的特性
white crystals or powder
使用
Cacodylic acid is used for dermatologic treatment in cronic eczema, anemia and as a tonic.
定義
ChEBI: The organoarsenic compound that is arsenic acid substituted on the central arsenic atom with two methyl groups.
一般的な説明
A colorless, odorless crystalline solid. Melting point 195-196°C. Toxic by ingestion and irritating to skin and eyes.
空気と水の反応
Hygroscopic. Water soluble.
反応プロフィール
CACODYLIC ACID is a weak acid. Dissolves in water to yield solutions containing more hydrogen ions than pure water contains and so having a pH less than 7.0. Is neutralized exothermically by all bases to produce water plus a salt. Reacts (but usually slowly) with active metals to form gaseous hydrogen and a metal salt. Such reactions occur in principle for the solid acid but are quite slow if the solid acid remains dry. The solid may absorb enough water from the air and dissolve sufficiently in CACODYLIC ACID to corrode or dissolve iron, steel, and aluminum parts and containers. Reacts with cyanide salts to generate gaseous hydrogen cyanide. Flammable and/or toxic gases and heat may be generated with diazo compounds, dithiocarbamates, isocyanates, mercaptans, nitrides, and sulfides. Also may react with sulfites, nitrites, thiosulfates (to give H2S and SO3), dithionites (SO2), to generate flammable and/or toxic gases and heat. Reaction with carbonates and bicarbonates generates a harmless gas (carbon dioxide) but still some heat. Can be oxidized exothermically by strong oxidizing agents and reduced by strong reducing agents; a wide variety of products is possible. May initiate polymerization reactions; may catalyze (increase the rate of) chemical reactions.
危険性
Toxic by ingestion.
健康ハザード
Chemical is essentially non-irritating in contact with skin or eyes. Ingestion causes arsenic poisoning, but symptoms are delayed.
火災危険
Behavior in Fire: May form toxic oxides of arsenic when heated.
輸送方法
UN1572 Cacodylic acid & UN1688 Sodium
Cacodylate, Hazard Class: 6.1; Labels: 6.1-Poisonous materials. UN3465 Organoarsenic compound, solid, n.o.s.,
Hazard Class: 6.1; Labels: 6.1-Poisonous materials,
Technical Name Required
純化方法
Recrystallise it from warm EtOH (3mL/g) by cooling and filtering. Dry it in a vacuum desiccator over CaCl2. It has also been recrystallised twice from propan-2-ol. [Koller & Hawkridge J Am Chem Soc 107 7412 1985, Beilstein 4 IV 3681.]
不和合性
A strong reducing agent. Incompatible
with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from
alkaline materials, strong bases, strong acids, oxoacids,
epoxides. Aqueous solution reacts violently with chemically active metals releasing toxic arsenic fumes.
Incompatible with oxidizers, sulfuric acid; caustics (strong
bases), reducing agents; ammonia, amines, isocyanates,
alkylene oxides; epichlorohydrin.
カコジル酸 上流と下流の製品情報
原材料
準備製品