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5-オキソ-L-Pro-L-Arg-L-Pro-L-Pro-L-Met-L-Glu-L-Glu-L-Glu-L-Glu-L-Glu-L-Ala-L-Tyr-Gly-L-Trp-L-Met-L-Asp-L-Phe-NH2

5-オキソ-L-Pro-L-Arg-L-Pro-L-Pro-L-Met-L-Glu-L-Glu-L-Glu-L-Glu-L-Glu-L-Ala-L-Tyr-Gly-L-Trp-L-Met-L-Asp-L-Phe-NH2 化学構造式
81123-06-0
CAS番号.
81123-06-0
化学名:
5-オキソ-L-Pro-L-Arg-L-Pro-L-Pro-L-Met-L-Glu-L-Glu-L-Glu-L-Glu-L-Glu-L-Ala-L-Tyr-Gly-L-Trp-L-Met-L-Asp-L-Phe-NH2
别名:
ガストリンIヘプタデカペプチド【ラット】;ガストリンI【ラット】;5-オキソ-L-Pro-L-Arg-L-Pro-L-Pro-L-Met-L-Glu-L-Glu-L-Glu-L-Glu-L-Glu-L-Ala-L-Tyr-Gly-L-Trp-L-Met-L-Asp-L-Phe-NH2;ガストリン-1, ラット;ガストリンI ラット
英語名:
Gastrin I (rat)
英語别名:
GASTRIN I;GASTRIN (RAT);GASTRIN-1, RAT;GASTRIN I (RAT);GASTRIN (1-17), RAT;GASTRIN, RAT (1-17);GASTRIN I RATGASTRIN;PYR-RPPMEEEEEAYGWMDF-NH2;Gastrin-17 I (rat) (9CI);Gastrin I, rat, ≥97% (HPLC)
CBNumber:
CB4351027
化学式:
C94H128N22O31S2
分子量:
2126.28
MOL File:
81123-06-0.mol

5-オキソ-L-Pro-L-Arg-L-Pro-L-Pro-L-Met-L-Glu-L-Glu-L-Glu-L-Glu-L-Glu-L-Ala-L-Tyr-Gly-L-Trp-L-Met-L-Asp-L-Phe-NH2 物理性質

比重(密度) :
1.55±0.1 g/cm3(Predicted)
貯蔵温度 :
−20°C
溶解性:
Soluble in DMSO
外見 :
Solid
酸解離定数(Pka):
4.19±0.10(Predicted)

安全性情報

WGK Germany  3

5-オキソ-L-Pro-L-Arg-L-Pro-L-Pro-L-Met-L-Glu-L-Glu-L-Glu-L-Glu-L-Glu-L-Ala-L-Tyr-Gly-L-Trp-L-Met-L-Asp-L-Phe-NH2 価格 もっと(6)

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入
富士フイルム和光純薬株式会社(wako) W01LKTG0179 ガストリン-1, ラット
Gastrin-1, rat 		81123-06-0 0.5mg ￥30500 2024-03-01 購入
富士フイルム和光純薬株式会社(wako) W01LKTG0179 ガストリン-1, ラット
Gastrin-1, rat 		81123-06-0 1mg ￥50800 2024-03-01 購入
富士フイルム和光純薬株式会社(wako) W01LKTG0179 ガストリン-1, ラット
Gastrin-1, rat 		81123-06-0 2.5mg ￥97400 2024-03-01 購入
Sigma-Aldrich Japan G1276 ガストリンI ラット ≥97% (HPLC)
Gastrin I rat ≥97% (HPLC)		 81123-06-0 250μg ￥93700 2024-03-01 購入
Sigma-Aldrich Japan G1276 ガストリンI ラット ≥97% (HPLC)
Gastrin I rat ≥97% (HPLC)		 81123-06-0 1mg ￥171000 2024-03-01 購入

5-オキソ-L-Pro-L-Arg-L-Pro-L-Pro-L-Met-L-Glu-L-Glu-L-Glu-L-Glu-L-Glu-L-Ala-L-Tyr-Gly-L-Trp-L-Met-L-Asp-L-Phe-NH2 化学特性,用途語,生産方法

使用

Gastrin I (rat) has been used in a study for gastrin stimulation in rats to determine the expression of histidine decarboxylase and histamine metabolism in gastric oxyntic mucosa during conditions of hypergastrinemia and carcinoid tumor. It has also been used for preabsorption of anti-gastrin antibody prior to immunohistochemical assay in rats.

一般的な説明

Gastrin is a pyloric antral hormone, which is a small biologically active peptide thatis synthesized as a precursor. It is found to be produced in antral G cells.

Biochem/physiol Actions

Gastrin plays a crucial role in the maintenance of architecture and function of oxyntic mucosa of stomach, which is involved in the secretion of acid. It also triggers the secretion of acid into the gastric lumen. Continuous increased plasma levels of gastrin or hypergastrinemia, may be involved in gastrointestinal carcinogenesis, especially if it is accompanied with inflammation. The release of this peptide is suppressed during distention, which is a result of omatostatin and intrinsic cholinergic pathways. In rats, this peptide maintains gastric mucosal integrity through the up-regulation of cyclooxygenase-2 which is, in part, mediated by heparin-binding epidermal growth factor-like growth factor (HB-EGF).

5-オキソ-L-Pro-L-Arg-L-Pro-L-Pro-L-Met-L-Glu-L-Glu-L-Glu-L-Glu-L-Glu-L-Ala-L-Tyr-Gly-L-Trp-L-Met-L-Asp-L-Phe-NH2 上流と下流の製品情報

原材料

準備製品

5-オキソ-L-Pro-L-Arg-L-Pro-L-Pro-L-Met-L-Glu-L-Glu-L-Glu-L-Glu-L-Glu-L-Ala-L-Tyr-Gly-L-Trp-L-Met-L-Asp-L-Phe-NH2 生産企業

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81123-06-0(5-オキソ-L-Pro-L-Arg-L-Pro-L-Pro-L-Met-L-Glu-L-Glu-L-Glu-L-Glu-L-Glu-L-Ala-L-Tyr-Gly-L-Trp-L-Met-L-Asp-L-Phe-NH2)キーワード:

オキシントモズジュリン 5-オキソ-L-Pro-Gly-L-Pro-L-Trp-L-Leu-L-Glu-L-Glu-L-Glu-L-Glu-L-Glu-L-Ala-L-Tyr-Gly-L-Trp-L-Leu-L-Asp-L-Phe-NH2 5-オキソ-L-Pro-L-Arg-L-Pro-L-Pro-L-Met-L-Glu-L-Glu-L-Glu-L-Glu-L-Glu-L-Ala-L-Tyr-Gly-L-Trp-L-Met-L-Asp-L-Phe-NH2 Nα-(α-アスパルチル)-L-フェニルアラニンアミド
  • 81123-06-0
  • GASTRIN (RAT)
  • GASTRIN, RAT (1-17)
  • PYR-ARG-PRO-PRO-MET-GLU-GLU-GLU-GLU-GLU-ALA-TYR-GLY-TRP-MET-ASP-PHE-NH2
  • PYR-RPPMEEEEEAYGWMDF-NH2
  • PGLU-ARG-PRO-PRO-MET-GLU-GLU-GLU-GLU-GLU-ALA-TYR-GLY-TRP-MET-ASP-PHE-NH2
  • 5-Oxo-L-Pro-L-Arg-L-Pro-L-Pro-L-Met-L-Glu-L-Glu-L-Glu-L-Glu-L-Glu-L-Ala-L-Tyr-Gly-L-Trp-L-Met-L-Asp-L-Phe-NH2
  • Gastrin I heptadecapeptide【rat】
  • GASTRIN (1-17), RAT
  • GASTRIN I (RAT)
  • GASTRIN-1, RAT
  • GASTRIN I
  • GASTRIN I RATGASTRIN
  • PYR-ARG-PRO-PRO-MET-GLU-GLU-GLU-GLU-GLU-ALA-TYR-GLY-TRP-MET-ASP-PHE-NH2 USP/EP/BP
  • Gastrin I, rat, ≥97% (HPLC)
  • Gastrin-17 I (rat) (9CI)
  • ガストリンIヘプタデカペプチド【ラット】
  • ガストリンI【ラット】
  • 5-オキソ-L-Pro-L-Arg-L-Pro-L-Pro-L-Met-L-Glu-L-Glu-L-Glu-L-Glu-L-Glu-L-Ala-L-Tyr-Gly-L-Trp-L-Met-L-Asp-L-Phe-NH2
  • ガストリン-1, ラット
  • ガストリンI ラット
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