아자시린
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아자시린 속성
- 녹는점
- 146-162° (dec)
- 알파
- D27.5 -0.5° (c = 8.46% in H2O at pH 5.18)
- 끓는 점
- 303.75°C (rough estimate)
- 밀도
- 1.5830 (rough estimate)
- 굴절률
- 1.6190 (estimate)
- 저장 조건
- 2-8°C
- 용해도
- H2O: 50 mg/mL, 투명, 노란색
- 물리적 상태
- 동결건조된 분말
- 산도 계수 (pKa)
- 8.55(at 25℃)
- 색상
- EtOH(aq)의 밝은 노란색 바늘
- Merck
- 13,902
- BRN
- 1726602
- IARC
- 2B (Vol. 10, Sup 7) 1987
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | T | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 25-40 | ||
| 안전지침서 | 53-36/37/39-45 | ||
| 유엔번호(UN No.) | UN 3462 6.1/PG 3 | ||
| WGK 독일 | 3 | ||
| RTECS 번호 | VT9625000 | ||
| F 고인화성물질 | 10 | ||
| 위험 등급 | 6.1(b) | ||
| 포장분류 | III | ||
| 유해 물질 데이터 | 115-02-6(Hazardous Substances Data) | ||
| 독성 | LD50 in mice, rats (mg/kg/day): 150, 170 orally (Sternberg, Philips) |
아자시린 C화학적 특성, 용도, 생산
화학적 성질
Light-yellow needles from EtOH.용도
antineoplastic, amino acid antagonist정의
ChEBI: A carboxylic ester resulting from the formal condensation of the carboxy group of diazoacetic acid with the alcoholic hydroxy group of L-serine. An antibiotic produced by a Streptomyces species.일반 설명
Pale yellow to green crystals. Used as an antifungal agent.공기와 물의 반응
Very soluble in water.반응 프로필
AZASERINE is incompatible with acids.위험도
Toxic; possible carcinogen; neoplastigenic; tumorigenic; poison; teratogen; mutagen.Safety Profile
Suspected carcinogen with experimental carcinogenic, neoplastigenic, and tumorigenic data. Poison by ingestion, intraperitoneal, and subcutaneous routes. An experimental teratogen. Other experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx.Purification Methods
Crystallise azaserine from 90% EtOH. Also dissolve it in H2O, filter it through Supercel and add EtOH to give azaserine as pale yellow crystals. [Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 1 pp 75-76 1961, Curphey & David J Org Chem 43 4666 1978, Beilstein 4 IV 3124.]아자시린 준비 용품 및 원자재
원자재
준비 용품
아자시린 공급 업체
글로벌( 92)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
fandachem@gmail.com | China | 9341 | 55 |
| career henan chemical co | +86-0371-86658258 15093356674; |
factory@coreychem.com | China | 29826 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 |
1026@dideu.com | China | 27894 | 58 |
| BOC Sciences | 16314854226; +16314854226 |
inquiry@bocsci.com | United States | 19743 | 58 |
| Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 |
sales@chemhifuture.com | China | 3136 | 58 |
| ZHEJIANG JIUZHOU CHEM CO., LTD | +86-0576225566889 +86-13454675544 |
admin@jiuzhou-chem.com；jamie@jiuzhou-chem.com；alice@jiuzhou-chem.com | China | 19949 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 |
market18@leapchem.com | China | 43348 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 |
product@acmec-e.com | China | 33350 | 58 |
| Aladdin Scientific | +1-833-552-7181 |
sales@aladdinsci.com | United States | 57511 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 |
3bsc@sina.com | China | 15848 | 69 |
아자시린 관련 검색:
아자시린 다이아조메테인(디아조메탄)
L-Lysine
2(3H)-Furanone,3-aminodihydro-(8CI,9CI)
ARSENAZO I
Phosphatidylserine
Decanedihydrazide
(S)-2-Amino-3-methoxypropanoic acid
O-ACETYL-L-SERINE
Ethyl diazoacetate
DL-O-METHYLSERINE
thrazarine
AZASERINE-HYPOXANTHINE (50X) GAMMA- IRRA
AZASERINE UN2811-III
AZASERINE-HYPOXANTHINE,Azaserine-Hypoxanthine 50x