3,5-디클로로아닐린
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3,5-디클로로아닐린 속성
- 녹는점
- 46-52 °C (lit.)
- 끓는 점
- 259-260 °C/741 mmHg (lit.)
- 밀도
- 1.58
- 굴절률
- 1.6000 (estimate)
- 인화점
- >230 °F
- 저장 조건
- Store below +30°C.
- 용해도
- 0.78g/L
- 산도 계수 (pKa)
- pK1:2.37(+1) (25°C)
- 물리적 상태
- 수정 같은
- 색상
- 짙은 회색
- 수용성
- 0.6g/L(26℃)
- BRN
- 636492
- LogP
- 2.9 at 20-25℃
- CAS 데이터베이스
- 626-43-7(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | T,N,Xi | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 23/24/25-33-50/53 | ||
| 안전지침서 | 28-36/37-45-60-61-28A | ||
| 유엔번호(UN No.) | UN 3442 6.1/PG 2 | ||
| WGK 독일 | 3 | ||
| F 고인화성물질 | 8 | ||
| 위험 참고 사항 | Irritant | ||
| TSCA | Yes | ||
| 위험 등급 | 6.1 | ||
| 포장분류 | II | ||
| HS 번호 | 29214210 | ||
| 유해 물질 데이터 | 626-43-7(Hazardous Substances Data) | ||
| 기존화학 물질 | KE-10065 |
3,5-디클로로아닐린 C화학적 특성, 용도, 생산
화학적 성질
white to brown crystals or needle crystal, soluble in ethanol, ether, diethyl carbonate, insoluble in water, high toxicity, corrosive.용도
Dichlorobenzenamine is used in the synthesis of effective inhibitors of plant δ1-pyrroline-4-carboxylate reductase. Also used in the preparation of anti-tumor agents based upon diaryl urea derivatives.주요 응용
3,5-Dichloroaniline is used in the production of pesticides, dyes and pharmaceuticals. 3,5-Dichloroaniline is an intermediate in the production of fungicides fumonisin, isoxaflutole, vinblastine and myclobutanil.제조 방법
synthesis of 3,5-Dichloroaniline: Add 25% hydrochloric acid and o-nitroaniline in the reaction kettle, turn on the stirring, pass chlorine gas for chlorination at 10-20℃ and negative pressure, after passing chlorine gas, continue to stir for 15min, then filter, and wash the filter cake with water to neutral, that is, 2,4-dichloro-6-nitroaniline.In another reaction kettle add industrial ethanol, under stirring, then add 2,4-dichloro-6-nitroaniline, add 95% H2SO4 below 40°C, cool to 15°C, add sodium nitrite in batches, after adding sodium nitrite, continue to hold the reaction at 15°C for 4h, then put the material into denitration kettle, slowly heat to reflux temperature 80°C and keep reflux for 2h, then raise the temperature to evaporate ethanol, and then distill the ethanol. Liquid material into the distillation kettle for water distillation, distillation of the resulting oil and water material for stratification, to obtain 3,5-dichloronitrobenzene.
Put a certain amount of water and 3,5-dichloronitrobenzene in the reaction kettle, raise the temperature to reflux under stirring, add a certain concentration of sodium disulfide solution drop by drop in 1h, and keep reflux for 3h, rest stratification, the lower layer of oily material washed with hot water to obtain 3,5-dichloroaniline.
3,5-디클로로아닐린 준비 용품 및 원자재
원자재
2,4-DICHLORO-6-NITROANILINE
2-니트로아닐린
3,5-디클로로나이트로벤젠
weak
Sodium disulfide
p-Dichlorobenzene
1-브로모-3,5-디클로로벤젠
3,5-dichlorobenzamide
Industrial ethanol
1,3,5-트리클로로벤젠
1,2-디클로로벤젠
2,6-디클로로아닐린
4-나이트로아닐린
2,6-디클로로-4-니트로아닐린
준비 용품
3,5-디클로로아닐린 공급 업체
글로벌( 368)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21688 | 55 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
| Zhejiang ZETian Fine Chemicals Co. LTD | 18957127338 |
stella@zetchem.com | China | 2141 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Shanghai Worldyang Chemical Co.,Ltd. | ,+86-21-56795779; +8613651600618 |
sales@worldyachem.com | China | 879 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 |
sales@amoychem.com | China | 6387 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 |
linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Standardpharm Co. Ltd. | 86-714-3992388 |
overseasales1@yongstandards.com | United States | 14336 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 |
sales@chemdad.com | China | 39916 | 58 |