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| | Tris(4-fluorophenyl)phosphine Basic information |
| | Tris(4-fluorophenyl)phosphine Chemical Properties |
| Melting point | 79-83 °C(lit.) | | Boiling point | 160°C/0.1mmHg(lit.) | | storage temp. | Inert atmosphere,Room Temperature | | form | Crystalline Powder | | color | White to very slightly yellow | | Water Solubility | Insoluble in water. | | Sensitive | Air Sensitive | | BRN | 919838 | | InChI | InChI=1S/C18H12F3P/c19-13-1-7-16(8-2-13)22(17-9-3-14(20)4-10-17)18-11-5-15(21)6-12-18/h1-12H | | InChIKey | GEPJPYNDFSOARB-UHFFFAOYSA-N | | SMILES | P(C1=CC=C(F)C=C1)(C1=CC=C(F)C=C1)C1=CC=C(F)C=C1 | | CAS DataBase Reference | 18437-78-0(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | HazardClass | IRRITANT | | HS Code | 29319090 |
| | Tris(4-fluorophenyl)phosphine Usage And Synthesis |
| Chemical Properties | white to light yellow crystal powde | | Uses | Ligand for rhodium-catalyzed oxygenative addition to terminal alkynes for a greener synthesis esters, amides, and carboxylic acids.
Rhodium-Catalyzed Oxygenative Addition to Terminal Alkynes for the Synthesis of Esters, Amides, and Carboxylic Acids | | Uses | Tris(4-fluorophenyl)phosphine, is an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff. | | Uses | Tris(4-fluorophenyl)phosphine (TFPP) and tris(2,2,2- trifluoroethyl) phosphite (TTFP) were used as flame-retarding additives in Li-ion battery clectrolytes.
Ligand for rhodium-catalyzed oxygenative addition to terminal alkynes for a greener synthesis esters, amides, and carboxylic acids. | | Preparation | with 4-bromofluorobenzene, magnesium, and phosphorous (III) trichloride.3 Alternatively, reduction of tris(4-fluorophenyl)phosphine oxide with an iron catalyst. | | General Description | We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product has been enhanced for catalytic efficiency. Click here for more information. | | Synthesis | Tris (4-fluorophenyl)phosphine oxide could be used as a starting material to synthesize Tris(4-fluorophenyl)phosphine. Into the reactor were added 0.2 mmol of tris(4-fluorophenyl)phosphine oxide, 0.36 mmol of trifluoroacetic anhydride, and 1 ml of dioxane as a solvent. Stir at room temperature under a nitrogen atmosphere for 30 min; after the reaction, continue adding 0.2 mmol of sodium bicarbonate, 0.24 mmol of 15-Crown-5, and 1.2 mmol of sodium hydride under a nitrogen environment. Under 150 ℃, stir for 24 hours, stop the reaction, cool to room temperature, and distilled under reduced pressure to remove the solvent. The crude product is separated by column chromatography to obtain Tris(4-fluorophenyl)phosphine with a yield of 74%.
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| | Tris(4-fluorophenyl)phosphine Preparation Products And Raw materials |
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